SPEAKER
Prof Ioannis XENARIOS
Director Swiss-Prot & Vital-IT group
SIB- Swiss Institute of Bioinformatics
Center for Integrative Genomics
University of Lausanne, Lausanne,
Switzerland
HOST:
Department of Oncology
RESPONSIBLE LIH SCIENTISTS:
Dr Francisco Azuaje
(francisco.azuaje@lih.lu)
www.lih.lu
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SYSTEMS-LEVEL MODELING BETWEEN BIOCURATION, PREDICTIONS AND VALIDATIONS
ABSTRACT
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In silico modeling how cells react,
respond to its genetics and its environment
is certainly a great vision of the
computational field. The ability to mix
different type of expertises ranging from
biocuration to computational system
modeler is also a way to establish a map
of our current knowledge but also identifying
the lack
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off it (in most cases). The presentation will take a tour between
constructing knowledge executable model
and using these to predict and ultimately
validate the discovery made by these
models. The model is based on the tumor
microenvironment and the ability to
transform and revert certain cellular
phenotypes.
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