SPEAKER
Prof Ioannis XENARIOS
Director Swiss-Prot & Vital-IT group SIB- Swiss Institute of Bioinformatics Center for Integrative Genomics University of Lausanne, Lausanne, Switzerland


HOST:
Department of Oncology


RESPONSIBLE LIH SCIENTISTS:
Dr Francisco Azuaje
(francisco.azuaje@lih.lu)

www.lih.lu


SYSTEMS-LEVEL MODELING BETWEEN BIOCURATION, PREDICTIONS AND VALIDATIONS

ABSTRACT

In silico modeling how cells react, respond to its genetics and its environment is certainly a great vision of the computational field. The ability to mix different type of expertises ranging from biocuration to computational system modeler is also a way to establish a map of our current knowledge but also identifying the lack off it (in most cases). The presentation will take a tour between constructing knowledge executable model and using these to predict and ultimately validate the discovery made by these models. The model is based on the tumor microenvironment and the ability to transform and revert certain cellular phenotypes.


Supported by: