SPEAKER
Prof Jessica Tenenbaum
Assistant Professor, Department of
Biostatistics and Bioinformatics, Division of
Translational Biomedical Informatics,
Duke University School of Medicine,
Durham, NC, USA
HOST:
Department of Oncology
RESPONSIBLE LIH SCIENTISTS:
Dr Francisco Azuaje
(francisco.azuaje@lih.lu)
Léon-Charles TRANCHEVENT
(leon-charles.tranchevent@lih.lu)
www.lih.lu
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TRANSLATIONAL BIOINFORMATICS IN THE PRECISION MEDICINE ERA
ABSTRACT
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The field of translational bioinformatics
is at an exciting stage of progression.
The past decade has seen the establishment
of TBI as a widely recognized discipline
unto itself, and the launch of a
number of large-scale initiatives that TBI
has enabled around the globe. The
recent explosion of molecular data coupled
with clinical data on actual patients
holds the potential to define an entirely
new taxonomy of disease. In this new
taxonomy, disease would be classified
not solely by macroscopic symptoms
many of which have been observed for
centuries, but rather based on underlying
molecular and environmental causes.
This paradigm shift, enabled by novel
methods for the generation, storage,
analysis, and visualization of “big data”
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in biology and medicine, promises to do
nothing short of rewrite the textbook of
medicine moving forward. As technology
continues to advance, assay costs to
decrease, and as methods are further
refined, the next decade is likely to
feature increasingly pervasive examples
of applied translational bioinformatics,
both in healthcare and other areas of
day to day life. In this talk I will highlight
success stories and outstanding
achievements in, or enabled by, translational
bioinformatics. I will describe some
important caveats and obstacles we
face in this rapidly advancing field, as
well as some ideas on how to address
those hurdles. Finally, I will explore some
of the tremendous opportunities we
face in the years ahead.
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