SPEAKER
Prof Ido AMIT
Professor of Department of Immunology,
Weizmann Institute of Science, Rehovot, Israel
HOST:
Department of Infection and Immunity
RESPONSIBLE LIH SCIENTIST:
Dr Feng He (feng.he@lih.lu)
www.lih.lu
Supported by:
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THE POWER OF ONE: IMMUNOLOGY IN THE AGE
OF SINGLE CELL GENOMICS
ABSTRACT
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The immune system is a complex, dynamic and
plastic network composed of various interacting
cell types that are constantly sensing and
responding to environmental cues. From very
early on, the immunology field has invested great
efforts and ingenuity to characterize the various
immune cell types and elucidate their functions.
However, accumulating evidence indicates that
current technologies and classification schemes
are limited in their ability to account for the
functional heterogeneity of immune processes.
Single cell genomics hold the potential to
revolutionize the way we characterize
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complex immune cell assemblies and study
their spatial organization, dynamics, clonal
distribution, pathways, and crosstalk. This
emerging field can greatly affect basic and
translational research of the immune system.
I will discuss how recent single cell genomic
studies are changing our perspective of
various immune related pathologies from
cancer to neurodegeneration. Finally, I will
consider recent and forthcoming technological
and analytical advances in single cell genomics
and their potential impact on the future of
immunology research and immunotherapy.
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* Opposite Luxembourg Institute of Health, House of BioHealth, 29, rue Henri Koch L-4354 Esch/Alzette
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